Several medications containing Losartan are being recalled. (Black Press file photo)

Potential ‘human carcinogen’ leads to recall of Losartan-containing drugs

Health Canada is advising that there is no immediate risk to patients taking these medications

Multiple high blood pressure medications containing Losartan are being voluntarily recalled due to a “potentially human carcinogen,” Health Canada says.

Teva Canada, Apotex Inc., Pharmascience Inc,m and Pro Doc Limitée are recalling lots of Losartan-containing drugs because of the potential for a nitrosamine impurity, N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) – a potential human carcinogen meaning that long-term exposure could increase the potential risk of cancer.

As with previous recalls involving nitrosamine impurities, Health Canada is advising that there is no immediate risk to patients taking these medications since the potential risk of cancer is with long-term exposure to the impurities.

“Patients should not stop taking their medication unless advised to do so by their healthcare provider,” Health Canada says.

Teva Canada is voluntarily recalling two lots of combination Losartan/hydrochlorothiazide (HCTZ) tablets after testing of one lot identified levels of NMBA above what is considered reasonably safe if the drug were taken over a lifetime. Apotex Inc., Pharmascience Inc., and Pro Doc Limitée are voluntarily recalling multiple lots of Losartan-containing products as a precaution.

The Losartan active pharmaceutical ingredient (API) in all of the recalled products is manufactured by Hetero Labs Ltd. Unit 1, in India. These recalls represent all lots of drugs distributed in Canada that contain Losartan API manufactured at Hetero Labs Ltd. Unit 1.

Related: Children’s strawberry-flavoured medicines recalled due to faulty safety cap

Related: Brewer’s yeast recall for peanut allergies

Losartan is an angiotensin receptor blocker (ARB) drug, also known as a “sartan.” Sartans are a class of drugs used to treat patients with high blood pressure to help prevent heart attacks and stroke. They are also used in patients who have had heart failure or a recent heart attack. There have been multiple recalls of products containing another sartan, valsartan, in Canada and internationally since July 2018 because of nitrosamine impurities (see links below for more information).

There are alternative products currently available on the Canadian market.

Health Canada continues to monitor the supply situation. Health Canada encourages Canadians to visit drugshortagescanada.ca for information on drug shortages and discontinuances. Patients with questions or concerns about any drug they are taking, including on what to do if that drug is not readily available, should speak to their healthcare professional.

For a list of affected products, visit healthycanadians.gc.ca.


@VernonNews
newstips@vernonmorningstar.com

Like us on Facebook and follow us on Twitter.

Just Posted

VicPD investigates stabbing near Selkirk Montessori school

Victim in potentially life-threatening condition

Victoria man spots online photo of his totem pole 11 years after it was stolen

Mark Trueman restored the pole himself before it was stolen off of his property in Duncan

Fire crews called to home near Beacon Park

Victoria police and fire departments are on scene in the 900 block… Continue reading

VIDEO: Trudeau asks Canada to look to current, not past, actions on race

Liberal leader says he never spoke about the racist photo because he was embarrassed

Crime Stoppers most wanted for Greater Victoria for the week of September 17

Greater Victoria Crime Stoppers is seeking the public’s help in locating the… Continue reading

POLL: Should the province step in to upgrade the road to Bamfield?

The death of two University of Victoria students on a bus bound… Continue reading

Horvat paces Canucks to 6-1 pre-season win over Oilers

Vancouver improves to 3-1 in NHL exhibition action

Legislature gifts, clothing, travel need better control, B.C. auditor says

Audit follows suspensions of managers by Speaker Darryl Plecas

‘Really disturbing:’ Trudeau’s racist photos worry B.C. First Nation chief

Wet’suwet’en Chief concerned the photos will sow fear in Indigenous communities

‘Unacceptable’: What politicians have to say about Trudeau in blackface

Calgary Mayor Naheed Nenshi: ‘When I saw that picture last night, certainly it was a sucker-punch’

Island contestant competes on Great Canadian Baking Show

Andrea Nauta auditioned for the show before but was lucky second time around

VIDEO: B.C. man accused of assaulting sex worker loses temper in interrogation

Defence lawyer says statements made by accused Curtis Sagmoen should be deemed inadmissible

Most Read